Anyone using Razer Black Shark V2 gaming headset with SmartSDR? Mic profile setting?

The mic profile has no universal optimal setting. It is always dependent on your voice and individual preferences.

I would suggest going to YouTube and search for NM9P. Ken has some excellent videos on using Full Duplex (FDX) to set your mic equalization so that it sounds the way you want it to.

His method really beats asking others over the air. You tend to get conflicting reports based on the receiving stations' preferences.

You can even set up multiple profiles for the same mic to cover different uses, like DX, rag chewing, etc.