I have done several of the updates of the beta versions of 2.1 while remote.
I would caution you that sometimes things can go wrong
The fix is that you will need to remove power to reboot the radio.
So it should be OK to update Remotely if:
1. Your radio is set to Auto start when power is applied
2. You can remotely reboot the power to the radio
CAVEAT...the MAC address of your radio will change in V2.1
So if you are using SmartLink with a fixed DHCP IP allocation in your router based on MAC address you will need be able to remotely redefine your routing table to point the IP to the new MAC Address.
1. 2000 miles away - without radio?
2. the "more value" not exit in this version - yes, some nice feature but most cosmetics and (what we can't see) feature for the F64/66 TRX