What an amazing radio ...much more mind bending than I had expected. I just got a Flex 6500 and I'm running it on a Mac with Parallels/Window 10. . The radio works great in this environment and the SmartSDR spread out across the iMac monitor looks great. I'm having trouble with some I/O issues...both audio/DAX and reconciling the windows com ports, the Flex virtual com ports and trying to connect to USB devices that live on the Mac side. For example, I'm setting up Fldigi. It was fairly easy to set up com port communication and rig control, frequency exchange etc works. The Fldigi configurator Audio tab should let you select DAX I/O through Port Audio, but it is greyed out. This is probably a parallels/Windows issue. Getting com ports straight for N1MM and integrating Winkeyer is going through a slow trial and error process. I'd love to hear from others who have worked through these issues in the Mac/Parallels/Windows setting.