This behavior has just started, a couple of days or so after installing the v2,1,33. Since it also affects the keyboard at the same time, I'm dubious that it's SmartSDR causing the problem. I can work around it by pulling and replugging the USB cable (on both devices). Looking through the device manager, nothing obvious seems in error. Has anyone else had this problem and know a way to fix it? I'm more suspicious of a Win 10 driver issue, but have no way to troubleshoot that.