Commander 14.0.8, which was publicly released on May 28, was tested with SmartSDR 2.5.0 and SmartSDR 3.0.25. I used the latter to make many QSOs; it performed flawlessly with my 6500
Today, Flex publicly released SmartSDR 2.5.1 and SmartSDR 3.0.27, neither of which I had the opportunity to test beforehand. I successfully made a few FT8 QSOs with each release. In both cases, I initially encountered a failure of my 6500 to activate my amplifier, which I worked around by setting the Transmit Profile selector to SO2R_TX1. I also observed several instances of "spontaneous disconnection" between Commander and SmartSDR, followed by an automatic reconnection; I'll be adding some diagnostics to Commander to track down the root cause of this behavior, and will report the results here.
Note that Commander 14.0.8 also supports SmartSDR 2.4.9.